<p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Methyl-Guard Plus® Details</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif"><br></font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Thorne’s Methyl-Guard Plus features betaine (trimethylglycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif"><br></font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">&nbsp;</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif"><br></font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Benefits of Thorne’s Methyl-Guard Plus:</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif"><br></font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Nutritional support for individuals who have MTHFR gene mutations*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Enhanced cellular energy production fights fatigue*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Promotes fat metabolism and lean body composition*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Supports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Promotes liver detoxification of many substances, including hormones like estrogen*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">&nbsp;</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif"><br></font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Why is methylation important:</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif"><br></font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif"><br></font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Cardiovascular health</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Cellular energy production</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Fat metabolism</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Neurological function</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">DNA production</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Liver detoxification processes</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Eye health</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Histamine balance</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">&nbsp;</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif"><br></font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Who can benefit from Thorne's Methyl-Guard Plus:</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif"><br></font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Individuals with mutations to MTHFR and other genes that adversely affect methylation*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Women seeking support for estrogen metabolism and bone health*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">&nbsp;</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif"><br></font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Features of Thorne's Methyl-Guard Plus:</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif"><br></font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Betaine, also known as trimethylglycine, is a superior methyl donor&nbsp;</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Active forms of vitamins B2 and B6 – key cofactors in methylation processes</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work*</font></p><p style=""><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard®</font></p><ul><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Betaine contributes to normal homocysteine metabolism</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Riboflavin contributes to normal energy-yielding metabolism</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Riboflavin contributes to normal functioning of the nervous system</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Riboflavin contributes to the maintenance of normal mucous membranes, skin, vision &amp; red blood cells</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Riboflavin contributes to the normal metabolism of iron</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Riboflavin contributes to the protection of cells from oxidative stress</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Riboflavin contributes to the reduction of tiredness and fatigue</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B6 contributes to normal homocysteine,&nbsp; energy-yielding , protein and glycogen metabolism</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B6 contributes to normal psychological function</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B6 contributes to normal red blood cell formation</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B6 contributes to the normal function of the immune &amp; nervous system</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B6 contributes to the reduction of tiredness and fatigue</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B6 contributes to the regulation of hormonal activity</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B6 contributes to normal cysteine synthesis</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Folate contributes to maternal tissue growth during pregnancy</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Folate contributes to normal amino acid synthesis</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Folate contributes to normal blood formation</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Folate contributes to normal homocysteine metabolism</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Folate contributes to normal psychological function</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Folate contributes to the normal function of the immune system</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Folate contributes to the reduction of tiredness and fatigue</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Folate has a role in the process of cell division</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Supplemental folic acid intake increases maternal folate status. Low maternal folate status is a risk factor in the development of neural tube defects in the developing foetus.</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B12 contributes to normal functioning of the nervous &amp; immune system</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B12 contributes to normal psychological function</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B12 contributes to normal energy-yielding &amp; homocysteine metabolism</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B12 contributes to normal red blood cell formation</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B12 contributes to the reduction of tiredness and fatigue</font></li><li><font color="#1b0c31" face="noto-sans, Noto Sans, Helvetica, Arial, sans-serif">Vitamin B12 has a role in the process of cell division</font></li></ul>