<h3>The connection between Cortisol and Sleep:</h3><p>Cortisol production is generally at its peak in the early morning and gradually declines over the course of the day to its lowest point right before sleep. Cortisol awakening response (CAR), the natural rise in cortisol secretion immediately after awakening can be influenced and blunted by sleep quality and total sleep time. (Vargas 2014, Fekedulegen 2018) Trouble falling asleep, and frequent waking can be common with increased cortisol levels. (Vgontzas 2001)</p><p>Cortisol, often referred to as the “stress hormone,” is produced by the adrenal cortex in response to signals from the hypothalamus and pituitary gland, as part of the hypothalamic-pituitary-adrenal (HPA) axis. Cortisol is perhaps the most important hormone involved in the adaptation process.</p><p>Upon exposure to acute stressors, cortisol secretion can generally help maintain homeostasis in the body. Because of its central role as a “first responder” and its capability to modulate multiple critical physiological functions, cortisol is often seen as the bridge between stress and its health consequences.</p><p>Cortisol Manager has been formulated with stress-reducing ingredients and botanicals to promote relaxation, help alleviate fatigue, and support healthy cortisol levels.* By balancing cortisol levels, Cortisol Manager Allergen Free can help reduce stress, which supports a restful night's sleep without diminishing daytime alertness.* Cortisol Manager Allergen-Free is formulated with:</p><ul> <li>Ashwagandha (Sensoril brand)</li></ul><ul> <li>L-theanine</li></ul><ul> <li>Magnolia</li></ul><ul> <li>Epimedium</li></ul><ul> <li>Phosphatidylserine</li></ul>